What does tricyclic antidepressant mean?

Definitions for tricyclic antidepressant
tri·cyclic antide·pres·sant

This dictionary definitions page includes all the possible meanings, example usage and translations of the word tricyclic antidepressant.

Princeton's WordNet

  1. tricyclic, tricyclic antidepressant, tricyclic antidepressant drugnoun

    an antidepressant drug that acts by blocking the reuptake of norepinephrine and serotonin and thus making more of those substances available to act on receptors in the brain

Wikipedia

  1. Tricyclic antidepressant

    Tricyclic antidepressants (TCAs) are a class of medications that are used primarily as antidepressants, which is important for the management of depression. They are second-line drugs next to SSRIs. TCAs were discovered in the early 1950s and were marketed later in the decade. They are named after their chemical structure, which contains three rings of atoms. Tetracyclic antidepressants (TeCAs), which contain four rings of atoms, are a closely related group of antidepressant compounds. Although TCAs are sometimes prescribed for depressive disorders, they have been largely replaced in clinical use in most parts of the world by newer antidepressants such as selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs) and norepinephrine reuptake inhibitors (NRIs). Adverse effects have been found to be of a similar level between TCAs and SSRIs. Another class of antidepressants, tetracyclic antidepressants, are also used around the world, and they have many similarities to the tricyclic antidepressants.

ChatGPT

  1. tricyclic antidepressant

    Tricyclic antidepressants (TCAs) are a class of medications primarily used for the treatment of depressive disorders. Named for their three-ring chemical structure, these drugs may also be used for conditions such as chronic pain, anxiety, and some neurological disorders. Tricyclic antidepressants work by increasing the levels of certain chemicals in the brain that help improve mood, though their precise mechanism of action is not fully understood. They are typically considered second or third line therapy due to their side effects and potential toxicity in overdose compared to other antidepressants.

Wikidata

  1. Tricyclic antidepressant

    Tricyclic antidepressants are heterocyclic chemical compounds used primarily as antidepressants. The TCAs were first discovered in the early 1950s and were subsequently introduced later in the decade; they are named after their chemical structure, which contains three rings of atoms. The tetracyclic antidepressants, which contain four rings of atoms, are a closely related group of antidepressant compounds. In recent times, the TCAs have been largely replaced in clinical use in most parts of the world by newer antidepressants such as the selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors and the norepinephrine reuptake inhibitors like reboxetine which typically have more favorable side-effects profiles, though they are still sometimes prescribed for certain indications.

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Numerology

  1. Chaldean Numerology

    The numerical value of tricyclic antidepressant in Chaldean Numerology is: 9

  2. Pythagorean Numerology

    The numerical value of tricyclic antidepressant in Pythagorean Numerology is: 6

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"tricyclic antidepressant." Definitions.net. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.definitions.net/definition/tricyclic+antidepressant>.

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